Class Ia Phosphatidylinositol 3-Kinase

A phosphatidylinositol 3-kinase subclass that includes enzymes formed through the heterodimerization of a p110 catalytic and a p85, p55, or p50 regulatory subunit. This subclass of enzymes is a downstream target of TYROSINE KINASE RECEPTORS and G PROTEIN-COUPLED RECEPTORS.

Also Known As:

Class Ia Phosphatidylinositol 3-Kinase, p110alpha Subunit; Class Ia Phosphatidylinositol 3-Kinase, p110beta Subunit; Class Ia Phosphatidylinositol 3-Kinase, p110delta Subunit; Class Ia Phosphatidylinositol 3-Kinase, p50alpha Subunit; Class Ia Phosphatidylinositol 3-Kinase, p55alpha Subunit; Class Ia Phosphatidylinositol 3-Kinase, p55gamma Subunit; Class Ia Phosphatidylinositol 3-Kinase, p85alpha Subunit; Class Ia Phosphatidylinositol 3-Kinase, p85beta Subunit; Class Ia Phosphatidylinositol 3-kinase, Regulatory, alpha Polypeptide; Class Ia Phosphatidylinositol 3-kinase, Regulatory, beta Polypeptide; Class Ia Phosphatidylinositol 3-kinase, Regulatory, gamma Polypeptide; Phosphatidylinositol 3-Kinase, Class Ia; Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide; Phosphoinositide-3-Kinase, Catalytic, beta Polypeptide; Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide; Phosphoinositide-3-Kinase, Regulatory Subunit 1; Phosphoinositide-3-Kinase, Regulatory Subunit 2; Phosphoinositide-3-Kinase, Regulatory Subunit 3; alpha-P85 Subunit, PI-3K; p110alpha Subunit, Class Ia Phosphatidylinositol 3-Kinase; p110beta Subunit, Class Ia Phosphatidylinositol 3-Kinase; p110delta Subunit, Class Ia Phosphatidylinositol 3-Kinase; p50alpha Subunit, Class Ia Phosphatidylinositol 3-Kinase; p55alpha Subunit, Class Ia Phosphatidylinositol 3-Kinase; p55gamma Subunit, Class Ia Phosphatidylinositol 3-Kinase; p85alpha Subunit, Class Ia Phosphatidylinositol 3-Kinase; p85beta Subunit, Class Ia Phosphatidylinositol 3-Kinase; Class Ia Phosphatidylinositol 3 Kinase; Class Ia Phosphatidylinositol 3 Kinase, p110alpha Subunit; Class Ia Phosphatidylinositol 3 Kinase, p110beta Subunit; Class Ia Phosphatidylinositol 3 Kinase, p110delta Subunit; Class Ia Phosphatidylinositol 3 Kinase, p50alpha Subunit; Class Ia Phosphatidylinositol 3 Kinase, p55alpha Subunit; Class Ia Phosphatidylinositol 3 Kinase, p55gamma Subunit; Class Ia Phosphatidylinositol 3 Kinase, p85alpha Subunit; Class Ia Phosphatidylinositol 3 Kinase, p85beta Subunit; Class Ia Phosphatidylinositol 3 Kinases; PI-3K alpha-P85 Subunit; Phosphatidylinositol 3 Kinase, Class Ia; Phosphoinositide 3 Kinase, Regulatory Subunit 1; Phosphoinositide 3 Kinase, Regulatory Subunit 2; Phosphoinositide 3 Kinase, Regulatory Subunit 3; p110alpha Subunit, Class Ia Phosphatidylinositol 3 Kinase; p110beta Subunit, Class Ia Phosphatidylinositol 3 Kinase; p110delta Subunit, Class Ia Phosphatidylinositol 3 Kinase; p50alpha Subunit, Class Ia Phosphatidylinositol 3 Kinase; p55alpha Subunit, Class Ia Phosphatidylinositol 3 Kinase; p55gamma Subunit, Class Ia Phosphatidylinositol 3 Kinase; p85alpha Subunit, Class Ia Phosphatidylinositol 3 Kinase; p85beta Subunit, Class Ia Phosphatidylinositol 3 Kinase; Class Ia Phosphatidylinositol 3-Kinases

Enzymes and Coenzymes: 1
- Enzymes: 155591
  - Transferases: 6719
    - Phosphotransferases: 43773
      - Phosphotransferases (Alcohol Group Acceptor)
        Phosphatidylinositol 3-Kinases: 1496
        Phosphatidylinositol 3-Kinase: 4225
        Class I Phosphatidylinositol 3-Kinases: 24
        Class Ia Phosphatidylinositol 3-Kinase: 69
        Phosphatidylinositol-4-Phosphate 3-Kinase: 1
        Class I Phosphatidylinositol 3-Kinases: 24
        Class Ia Phosphatidylinositol 3-Kinase: 69
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Intracellular Signaling Peptides and Proteins: 32
    - Phosphatidylinositol 3-Kinases: 1496
      - Phosphatidylinositol 3-Kinase: 4225
        Class I Phosphatidylinositol 3-Kinases: 24
        Class Ia Phosphatidylinositol 3-Kinase: 69
      - Phosphatidylinositol-4-Phosphate 3-Kinase: 1
        Class I Phosphatidylinositol 3-Kinases: 24
        Class Ia Phosphatidylinositol 3-Kinase: 69

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